Qaytarish

GM1 ga qarshi IgG avtoantitana

Kod:11004|CPT:83520|LOINC:43240-1

Sinonimlar
Иммуноглобулины (антитела) класса G.Anti-GM1 IgGAnti-ganglioside GM1 IgGGanglioside GM1 IgG autoantibodyIgG, total, serumImmunoglobulin G
KabiGM1 ga qarshi IgG avtoantitanalar

Tahlil ma'lumotlari

Tadqiqot usuli

  • Ferment bilan bog'langan immunosorbent analiz (ELISA)

Kutilayotgan natija topshirish vaqti

1 kun

Maxsus tayyorlik

  • Testing is not offered for patients in New York state.
  • Do not eat for 2–3 hours before the blood draw; water is allowed.
  • Avoid physical exertion and emotional stress for 30 minutes before collection.
  • Do not smoke during the 3 hours prior to phlebotomy.

Qanday foydalanish

GM1 IgG avtoantitana testi (Anti-GM1 IgG yoki anti-gangliozid GM1 IgG deb ham yuritiladi) zardobda GM1 ga qarshi IgG sinfidagi avtoantitanalarni kvalitatif aniqlaydi. Gangliozid maqsadlarga qarshi avtoantitanalarni baholash zarur bo‘lgan holatlarda qo‘llanadi. Tahlil ferment bilan bog‘langan immunosorbent analiz (ELISA) bilan bajariladi va natija kvalitatif shaklda beriladi.

Cheklovlar

GM1 (monosialotetraheksosilgangliozid) aniq ta’riflangan gangliozid antigenidir va ushbu tahlil zardobda shu nishonga yo‘naltirilgan IgG avtoantitanalarni baholaydi. Qo‘llaniladigan usul ferment bilan bog‘langan immunosorbent analiz (ELISA) bo‘lib, natijalar kvalitativdir. Topilmalar klinik baholash va zarur boshqa laborator ma’lumotlar bilan birgalikda talqin qilinadi.

O'lchov birligi%
Referens oraliq
MinMaks
8.1717.05
Ko'rsatmalar—

Namunangiz talablari

NamunangizZardob
ContainerOltin/yo'lbars qopqoqli probirka (SST, gel ajratgich)
Hajm0.3 mL (min 0.1 mL)
Saqlash tayyorlikMuzlatilgan

References

Chalah MA, et al. A comparison of four commercial tests for detecting anti-ganglioside antibodies in patients with well-characterized dysimmune peripheral neuropathies. 2016.Han TH, Kim DY, Park DW, Moon JH. Transient Isolated Lower Bulbar Palsy With Elevated Serum Anti-GM1 and Anti-GD1b Antibodies During Aripiprazole Treatment. Pediatr Neurol. 2017 Jan;66:96-99. PubMed 28341090Islam Z, Jacobs BC, van Belkum A, et al. Axonal variant of Guillain-Barré syndrome associated with Campylobacter infection in Bangladesh. Neurology. 2010 Feb 16;74(7):581-587. PubMed 20157160Kollewe K, Wurster U, Sinzenich T, et al. Anti-ganglioside antibodies in amyotrophic lateral sclerosis revisited. PLoS One. 2015 Apr 14;10(4):e0125339. PubMed 25875836Lei T, Siu KL, Kok KH, et al. Anti-ganglioside antibodies were not detected in human subjects infected with or vaccinated against 2009 pandemic influenza A (H1N1) virus. Vaccine. 2012 Mar 30;30(16):2605-2610. PubMed 22342549Mani B, et al. The Frequency of anti-Ganglioside Antibodies in Blood Donors Compared to Control Groups and Guillain-Barré Syndrome Patients. Poster presented at DAS, Dresden (GE). 2010.Sharma MB, Chaudhry R, Tabassum I, et al. The presence of Mycoplasma pneumonia infection and GM1 ganglioside antibodies in Guillain-Barré syndrome. J Infect Dev Ctries. 2011 Jul 4;5(6):459-474. PubMed 21727645Uncini A, Yuki N. Electrophysiologic and immunopathologic correlates in Guillain-Barré syndrome subtypes. Expert Rev Neurother. 2009 Jun;9(6):869-884. PubMed 19496690Uysalol M, Tatli B, Uzel N, Citak A, Aygün E, Kayaoğlu S. A Rare Form of Guillain-Barré Syndrome: A Child Diagnosed with Anti-GD1a and Anti-GD1b Positive Pharyngeal-Cervical-Brachial Variant. Balkan Med J. 2013 Sep;30(3):337-341. PubMed 25207134Wurster U, et al. Ganglioside Antibodies in Amyotrophic Lateral Sclerosis. Poster presented at DAS, Dresden (GE). 2009.

Wilson D. McGraw-Hill Manual of Laboratory and Diagnostic Tests 1st Ed. Normal, Illinois, 2007: 666 p.

Назаренко Г. И., Кишкун А. Клиническая оценка результатов лабораторных исследований. – М.: Медицина, 2000. – 533 с.

Рабсон А., Ройт А. Основы медицинской иммунологии. – М.: Мир, 2006. – 320 с.

Ярылин А. А. Иммунология. – М.: ГЭОТАР-Медиа, 2010. – 752 с.