Qaytarish

Epstein–Barr virusi (EBV) viral kapsid antigeniga (VCA) qarshi antikorlar, IgM

Kod:17063|CPT:86665|LOINC:5159-9

Sinonimlar
Антитела класса IgM к КБ вируса Эпштейна – Барриммуноглобулины класса M к капсидному белку вируса инфекционного мононуклеозаанти-VCA класса IgMAnti-VCA IgMAntibodies to Epstein–Barr virus viral capsid antigen, IgMEBV VCA IgMEBV VCA IgM antibodyEBV-VCA antibodies, IgMInfectious mononucleosis (EBV antibody to viral capsid antigen), IgM
KabiEBV VCA ga qarshi antikorlar, IgM

Tahlil ma'lumotlari

Tadqiqot usuli

  • Kimyoluminessent immunoanaliz (CLIA)
  • Ferment immunoanalizi (EIA)

Kutilayotgan natija topshirish vaqti

1–2 kun

Maxsus tayyorlik

  • Avoid smoking for at least 30 minutes before the blood sample is collected.

Qanday foydalanish

Ushbu test — EBV VCA IgM yoki anti‑VCA IgM deb ham ataladi — infeksion mononuklyozga mos keladigan o‘tkir yoki yaqinda kechgan birlamchi EBV infeksiyasini aniqlash uchun qo‘llanadi. Shuningdek, simptomlar ustma-ust tushganda mononuklyozga o‘xshash kasalliklarning boshqa sabablaridan EBVni farqlashga yordam beradi.

Cheklovlar

Epstein–Barr virusi (inson gerpesvirusi 4) asosan B limfotsitlarni zararlaydi va infeksion mononuklyoz hamda EBV bilan bog‘liq bir qator holatlar, jumladan nazofaringeal karsinoma, Burkitt limfomasi, Xodjkin kasalligi, og‘iz bo‘shlig‘ining tukli leyukoplakiya va B-hujayrali limfomalar bilan bog‘langan. Virus dunyo bo‘ylab keng tarqalgan va so‘lak orqali yuqadi; dastlabki infeksiyalarning ko‘pi bolalik yoki o‘smirlik davrida sodir bo‘ladi. Orofarin­geal epiteliy orqali kirgach, EBV gematogen yo‘l bilan tarqaladi va B-hujayralar proliferatsiyasini qo‘zg‘aydi, natijada tonsillalar va limfa tugunlarining kattalashuvi hamda splenomegaliya kuzatiladi; immunokompetent shaxslarda odatda infeksiya nazorat qilinadi va simptomlar susayadi. So‘ng EBV B-hujayralarning bir qismida latent holatda saqlanib qoladi va hujayraviy immunitet buzilganda (masalan, HIV infeksiyasi yoki iatrogen immunosupressiya) limfoproliferativ kasallik rivojlanishiga hissa qo‘shishi mumkin.

O'lchov birligiqualitative
Referens oraliq
MinMaks
03
Ko'rsatmalarWorkup of suspected infectious mononucleosis in patients with pharyngitis, fever, generalized lymph node enlargement, splenomegaly with or without hepatomegaly, and fatigue, Evaluation of athletes with possible infectious mononucleosis when splenic enlargement raises concern for exertion-related splenic rupture

Namunangiz talablari

NamunangizZardob
ContainerOltin/yo'lbars qopqoqli probirka (SST, gel ajratgich)
Hajm0.5 mL (min 0.2 mL)
Saqlash tayyorlikXona harorati, Sovutilgan, Muzlatilgan

References

Kasper DL, Braunwald E, Fauci A, Hauser S, Longo D, Jameson JL. Harrison's Principles of Internal Medicine. 16th ed. New York: McGraw-Hill; 2005.

Fischbach FT, Dunning MB. A Manual of Laboratory and Diagnostic Tests. 8th ed. Philadelphia: Lippincott Williams & Wilkins; 2008.

Kishkun AA. Immunologic and serologic studies in clinical practice. Moscow: MIA; 2006: 335–345.