Kreatinin, 24 soatlik siydik
Kod:7008
| Kabi | Kreatinin, 24 soatlik siydik |
|---|
Tahlil ma'lumotlari
Tadqiqot usuli
- Yaffe kinetik usuli
Kutilayotgan natija topshirish vaqti
1 kun
Maxsus tayyorlik
- Do not consume alcohol during the 24 hours before starting the collection.
- For 12 hours before collection, avoid spicy or salty foods and items that can discolor urine (such as beetroot or carrots).
- With clinician approval, hold diuretics for 48 hours before and throughout the 24-hour collection.
- Limit strenuous physical activity and emotional stress during the collection period.
Qanday foydalanish
Kreatinin, 24 soatlik siydik testi buyrakning ekskretor funksiyasini baholash va buyrak kasalligi aniqlangan yoki gumon qilingan bemorlarni kuzatishda qo‘llanadi. Boshqa vaqtli siydik tekshiruvlariga hamroh o‘lchov sifatida, 24 soatlik siydikdagi kreatinin yig‘imning to‘liqligi va tahlilga yaroqliligini tasdiqlashga yordam beradi. Bir vaqtda olingan qon zardobidagi kreatinin bilan birga talqin qilinganda, vaqtli siydik yig‘imidan olingan siydik kreatinini kreatinin klirensini taxminlash uchun ishlatilishi mumkin.
Cheklovlar
Kreatinin kreatin va fosfokreatindan, asosan skelet mushaklarida, qisqarishni ta’minlovchi energiya hosil bo‘lish jarayonlari davomida hosil bo‘ladi. Buyraklar kreatininni minimal kanalchalar reabsorbsiyasi bilan chiqaradi, natijada siydikdagi konsentratsiya qondagiga nisbatan o‘nlabdan yuzlab martagacha yuqori bo‘ladi. Bir individda kunma-kun kreatinin chiqarilishi nisbatan barqaror va mushak massasiga proportsional bo‘lib, jins va yosh bo‘yicha farqlarga olib keladi. Qon zardobidagi kreatinin va 24 soatlik siydikdagi kreatininni juft o‘lchash glomerulyar filtratsiya tezligini baholovchi ko‘rsatkich sifatida kreatinin klirensini hisoblash imkonini beradi; buyrak funksiyasi pasayganda vaqtli namunada chiqariladigan kreatinin miqdori kamayadi. Vaqtli siydikdagi kreatinin chiqarilishi nisbatan turg‘un bo‘lgani sababli, 24 soatlik siydik yig‘imlarining yetarliligini baholashda qo‘llanadi va buyrak kasalligini baholashda siydik oqsili yoki albumin bilan birga tez-tez buyuriladi.
| O'lchov birligi | mmol/24h |
|---|---|
| Referens oraliq | — |
| Ko'rsatmalar | Baseline or periodic screening of kidney function, Workup of suspected renal disease when edema (periorbital or lower extremity), urinary abnormalities, lumbar or flank pain, or voiding difficulties are present, Assessment in disorders that commonly involve the kidneys (hypertension, diabetes mellitus, systemic lupus erythematosus, vasculitis), Monitoring response to therapy in kidney disease, Confirmation that a 24-hour urine collection is complete before testing hormones or other analytes |
Natija og'ishlarining mumkin sabablari
Oshgan daraja
- ascorbic acid
- cefazolin
- cephalothin
- cefoxitin
- corticosteroids
- fluoxymesterone
- high meat intake
- methotrexate
- methyldopa
- nandrolone
- nitrofurantoin
- nitrofurazone
- oxymetholone
- physical activity
- prednisolone
- pregnancy
Pasaygan daraja
- anabolic steroids
- captopril
- ketoprofen
- quinapril
- thiazide diuretics
Namunangiz talablari
| Namunangiz | Urina |
|---|---|
| Container | Steril siydik idishi |
| Saqlash tayyorlik | Sovutilgan, Muzlatilgan |
References
Fischbach F.T., Dunning M.B. A Manual of Laboratory and Diagnostic Tests, 8th Ed. Lippincott Williams & Wilkins, 2008: 1344 p.