Trigliseridlar
Kod:8016|CPT:84478|LOINC:2571-8
| Kabi | Trigliseridlar |
|---|
Tahlil ma'lumotlari
Tadqiqot usuli
- Fermentativ usul
- Kolorimetrik / fotometrik usul
Kutilayotgan natija topshirish vaqti
1 kun
Maxsus tayyorlik
- Do not eat for 12 hours before the blood draw.
- Avoid vigorous exercise and significant emotional stress before collection.
- Refrain from smoking during the 30 minutes prior to collection.
Qanday foydalanish
Trigliseridlar testi (TG; qon lipidlari, neytral yog'lar) giperlipidemiyani baholash, lipemik yoki loyqa zardob/plazmaning sabablarini aniqlashtirish, taxmin qilingan xilomikronemiyani tekshirish va parhezni o'zgartirish yoki lipidlarni kamaytiruvchi farmakoterapiyaga javobni monitoring qilish uchun qo'llaniladi. Ko'tarilishlar gipotireoz, nefrotik sindrom, uglevodlarga sezgir gipertrigliseridemiya, glikogen saqlanish kasalligi, alkogol iste'moli buzilishi va birlamchi giperlipoproteinemiyalar (I, IIb, III, IV va V turlari) bilan kechishi mumkin. Judayam yuqori trigliserid darajalari pankreatit bilan bog'liq bo'ladi va alkogoldan suiiste'mol qilishda kuzatilishi mumkin; oshgan qiymatlar qandli diabetda ham kuzatiladi. Lipid panellarida LDL-xolesterinni (LDL-C) hisoblash uchun trigliserid konsentratsiyasi talab etiladi va umumiy aterosklerotik yurak-qon tomir xavfini baholashga hissa qo'shadi.
Cheklovlar
Trigliseridlar asosan yog' to'qimasida saqlanadi, ammo apolipoproteinlarga bog'langan lipoprotein zarralari tarkibida qonda aylanadi. Ovqat qabul qilingandan so'ng ortiqcha energiya esterifikatsiyalanib qadoqlangani sababli konsentratsiya oshadi; ochlikda energiya ehtiyojini qondirish uchun trigliseridlar safarbar qilinadi va oksidlanadi. Plazmada asosiy tashuvchilar juda past zichlikdagi lipoproteinlar (VLDL) va xilomikronlardir. Uzoq muddatli ko'tarilish aterosklerotik yurak-qon tomir kasalligi bilan bog'liq, og'ir gipertrigliseridemiya esa o'tkir pankreatit xavfini oshiradi. Juda yuqori trigliserid konsentratsiyalarida (>800 mg/dL) hisoblangan LDL-xolesterin ishonchsiz bo'ladi.
| O'lchov birligi | mg/dL | ||||
|---|---|---|---|---|---|
| Referens oraliq |
| ||||
| Ko'rsatmalar | Periodic cardiovascular risk evaluation in adults aged ≥20 years as part of a fasting lipid panel, at least every 5 years, Tracking the effect of lipid-lowering medications or reduced dietary fat intake, Evaluation of dyslipidemia in the setting of diabetes mellitus, Assessment in individuals with cardiovascular risk factors, including tobacco use; age (men ≥45 years, women ≥55 years); hypertension (≥140/90 mm Hg); family history of premature atherosclerotic cardiovascular disease (male first-degree relative <55 years, female <65 years); known ischemic heart disease, prior myocardial infarction, or stroke; overweight or obesity; alcohol use disorder; high consumption of animal/saturated fats; and a sedentary lifestyle, Pediatric screening between ages 2–10 years when there is a family history of hypercholesterolemia or premature cardiovascular disease |
Natija og'ishlarining mumkin sabablari
Oshgan daraja
- alcohol
- amiodarone
- beta-adrenergic blocking agents
- cholestyramine
- corticosteroids
- estrogens
- furosemide
- high-fat meal
- inadequate fasting
- oral contraceptives
- pregnancy
- spironolactone
- thiazide diuretics
Pasaygan daraja
- metformin
- statins
- strenuous exercise
Namunangiz talablari
| Namunangiz | Zardob |
|---|---|
| Container | Oltin/yo'lbars qopqoqli probirka (SST, gel ajratgich) |
| Hajm | 1 mL (min 0.7 mL) |
| Saqlash tayyorlik | Xona harorati, Sovutilgan, Muzlatilgan |