Qizamiq (rubeola) virusiga qarshi IgG antitanalari
Kod:17034|CPT:86765|LOINC:5244-9
| Kabi | Qizamiqqa qarshi antitanalar, IgG |
|---|
Tahlil ma'lumotlari
Tadqiqot usuli
- Kimyoluminessent immunoanaliz (CLIA)
- Ferment immunoanalizi (EIA)
Kutilayotgan natija topshirish vaqti
1–2 kun
Maxsus tayyorlik
- Label each specimen as acute or convalescent; submit acute and convalescent samples with separate requisitions
- Do not smoke for 30 minutes before blood collection
Qanday foydalanish
Qizamiq (rubeola) virusiga qarshi IgG antitanalari—Anti-Measles Virus IgG yoki Measles Virus Specific IgG deb ham ataladi—immunitetni yoki o‘tmishda ta’sirlanish yoki emlashga oid dalillarni hujjatlashtirish maqsadida serologik holatni aniqlash uchun qo‘llanadi. Ijobiy natija odatda avvalgi infeksiya yoki emlashni bildiradi va immunitetning yetarli laborator dalili sifatida qabul qilinadi, noaniq (equivocal) natija esa presumtiv immunitetni anglatmaydi. Hujjat bilan tasdiqlangan, yoshga mos emlash serologik natijalardan ustun qo‘yiladi; qizamiq komponenti mavjud vaksinaning ikki dozasini hujjatlashtirgan shaxslar presumtiv ravishda immun hisoblanadi va serologiya manfiy yoki noaniq bo‘lsa ham qo‘shimcha dozalarga muhtoj emas.
Cheklovlar
Qizamiq — nafas yo‘llari tomchilari orqali yuqadigan yuqori yuqumli paramiksovirus infeksiyasi. Dastlabki replikatsiya nafas yo‘llari shilliq qavati va orofarenksda yuz beradi. Klinik belgilarga isitma, quruq yo‘tal, fotofobiya bilan kechuvchi kon’yunktivit, rinit (koryza), tomoq og‘rig‘i va Koplik dog‘lari kiradi; so‘ngra sefalokaudal yo‘nalishda tarqaladigan makulopapulyoz toshma paydo bo‘ladi. Ko‘pchilik bemorlar bir necha hafta ichida tuzaladi; biroq taxminan 20% hollarda o‘rta otit, bronxit, pnevmoniya, diareya, ensefalit yoki ko‘rlik kabi asoratlar rivojlanadi. Kasallik kattalarda va immunodefisit, A vitamini yetishmovchiligi yoki ovqatlanish yetishmovchiligi bo‘lgan shaxslarda og‘irroq kechadi. Homiladorlik davridagi infeksiya tushish va muddatidan oldin tug‘ish xavfini oshiradi. Infeksiyadan so‘ng qizamiq virusiga xos IgM birinchi bo‘lib paydo bo‘ladi, bir necha kun ichida cho‘qqiga yetadi va keyingi haftalarda susayadi. IgG 2–4 haftadan so‘ng rivojlanadi va o‘n yillar davomida saqlanib, uzoq muddatli immunitetni ta’minlaydi. IgG emlashdan keyin ham hosil bo‘ladi, shuningdek, onadan o‘tgan IgG ayrim chaqaloqlarda 6–7 oylikkacha aniqlanishi mumkin.
| Referens oraliq |
| ||||
|---|---|---|---|---|---|
| Ko'rsatmalar | Evaluation of suspected acute or recent measles in the period 7–18 days after exposure, Assessment of measles immune status after natural infection or vaccination |
Namunangiz talablari
| Namunangiz | Zardob |
|---|---|
| Container | Oltin/yo'lbars qopqoqli probirka (SST, gel ajratgich) |
| Hajm | 0.5 mL (min 0.2 mL) |
| Saqlash tayyorlik | Xona harorati, Sovutilgan, Muzlatilgan |
References
Centers for Disease Control and Prevention. Manual for the Surveillance of Vaccine-Preventable Diseases. CDC website. https://www.cdc.gov/vaccines/pubs/surv-manual/index.html. Accessed June 2019.
Centers for Disease Control and Prevention. Measles (Rubeola): For Healthcare Professionals. CDC website. https://www.cdc.gov/measles/hcp/. Accessed June 2019.
McLean HQ, Fiebelkorn AP, Temte JL, Wallace GS; Centers for Disease Control and Prevention. Prevention of measles, rubella, congenital rubella syndrome, and mumps, 2013: summary recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2013 Jun 14;62(RR-04):1-34. PubMed 23760231