Qizamiqcha (rubella) virusiga qarshi IgG antitanalari
Kod:17003|CPT:86762|LOINC:5334-8
| Kabi | Qizamiqcha virusiga qarshi IgG antitanalari |
|---|
Tahlil ma'lumotlari
Tadqiqot usuli
- Kimyoluminessent immunoanaliz (CLIA)
- Immunoblot
Kutilayotgan natija topshirish vaqti
1 kun
Maxsus tayyorlik
- Avoid food for 2–3 hours before the blood draw; plain water is allowed.
- Do not smoke during the 30 minutes preceding specimen collection.
Qanday foydalanish
Qizamiqcha virusiga qarshi IgG antitanalari (anti‑rubella IgG; qizamiqchaga qarshi antitanalar) avvalgi infeksiya yoki immunizatsiyadan keyin yuzaga kelgan immunitetni aniqlash uchun, jumladan, homiladorlikdan oldingi va antenatal muntazam baholashlarda qo‘llaniladi. Shuningdek, u immunitetga ega bo‘lmagan va emlashdan foyda ko‘rishi mumkin bo‘lgan shaxslarni aniqlaydi. Bundan tashqari, tahlil noaniq yoki mos kelmaydigan serologik natijalarni aniqlashtirishga yordam beradi va homiladorlik vaqtida onaning infeksiyasi gumon qilinganda yoki tasdiqlanganda yangi tug‘ilgan chaqaloqlarda ehtimoliy tug‘ma qizamiqchani baholashni qo‘llab-quvvatlaydi.
Cheklovlar
O‘tkir qizamiqchadan so‘ng avval IgM paydo bo‘ladi, rubellaga xos IgG esa keyinroq rivojlanadi va odatda umrbod aniqlanib turadi, bu esa avvalgi infeksiya yoki vaksina bilan qo‘zg‘atilgan immunitetni ko‘rsatadi. Qizamiqcha odatda yengil, o‘z‑o‘zidan chegaralanuvchi toshmali kasallik bo‘lib, nafas yo‘llari tomchilari orqali yuqadi. Biroq, homiladorlikning birinchi trimestrida birlamchi infeksiya spontan abort, o‘lik tug‘ilish yoki ko‘p tizimli zararlanish bilan kechuvchi tug‘ma qizamiqcha sindromi xavfining yuqoriligi bilan bog‘liq; bular qatoriga sensorinevral eshitish yo‘qotilishi, katarakta, yurak anomaliyalari, mikrotsefaliya va jigar kasalligi kiradi. Immunoblot usullari rubella virusining alohida antigenlariga yo‘naltirilgan antitanalarni ko‘rsatishi mumkin, bu immun javobning xarakterini tavsiflashga yordam berishi mumkin.
| O'lchov birligi | index | ||||
|---|---|---|---|---|---|
| Referens oraliq |
| ||||
| Ko'rsatmalar | Clinical signs and symptoms compatible with rubella infection, Clarification of borderline or conflicting serologic results by enzyme immunoassay (EIA), Preconception or prenatal screening to document rubella immunity, Assessment of possible maternal rubella during pregnancy, including suspected rubella embryopathy, Workup of a potentially false‑positive rubella IgM due to cross‑reactivity (eg, Epstein–Barr virus, cytomegalovirus, parvovirus B19) or rheumatoid factor, Determination of immune status to guide vaccination or revaccination planning, Evaluation of newborns for congenital rubella syndrome when maternal infection is suspected or confirmed, Contribution to the differential diagnosis of a generalized exanthem (eg, measles, scarlet fever, allergic exanthema, enteroviral infection) |
Namunangiz talablari
| Namunangiz | Zardob |
|---|---|
| Container | Oltin/yo'lbars qopqoqli probirka (SST, gel ajratgich) |
| Hajm | 0.5 mL (min 0.2 mL) |
| Saqlash tayyorlik | Xona harorati, Sovutilgan, Muzlatilgan |