Ureaplasma/Mycoplasma hominis Culture
Code:18015|CPT:87109|LOINC:17852-5, 15388-2
| Includes | Ureaplasma urealyticum Mycoplasma hominis |
|---|
Analysis details
Methodology
- Culture on selective media
Expected Turnaround Time
1–2 days
Special Instructions
- Submit one specimen for each test ordered.
- Record the precise anatomic source of the specimen on the requisition.
- Include the specific test number on the request form.
- For women, collect prior to menstruation or 2–3 days after bleeding ends.
- For men, do not urinate for at least 3 hours before urethral swab collection.
How to use
The Ureaplasma/Mycoplasma hominis Culture is used to detect and identify Ureaplasma urealyticum and Mycoplasma hominis by culture in patient specimens. It assists in the workup of urogenital inflammation, including suspected urethritis, cervicitis, and prostatitis, and may be ordered as part of sexually transmitted infection evaluation. This assay, also known as Ureaplasma culture or Mycoplasma hominis genital culture, is often performed alongside testing for other STI pathogens because coinfections occur. Results are interpreted in conjunction with clinical findings and other laboratory data.
Limitations
Ureaplasma urealyticum and Mycoplasma hominis inhabit the genital tract and may be present in both symptomatic infection and asymptomatic colonization. Detection alone does not establish disease; significance depends on the clinical presentation and results of other tests. Coinfection with additional sexually transmitted pathogens is common, so concurrent screening is frequently appropriate. Culture may be negative despite true infection, and recent antimicrobial exposure can decrease recovery of the organisms. Findings should be interpreted together with clinical and other laboratory information.
| Reference interval | — |
|---|---|
| Indications | Routine STI screening in sexually active persons who forgo barrier protection, Workup of suspected urethritis, cervicitis, prostatitis, or other inflammatory conditions of the urogenital tract, Testing sexual partners of individuals with documented sexually transmitted infections |
Possible Causes of Abnormal Results
Decreased levels
- azithromycin
- ceftriaxone
- doxycycline
- erythromycin
Specimen Requirements
| Specimen | Saliva |
|---|---|
| Container | Saliva Collection Kit (PCR) |
| Storage Instructions | Refrigerated |
References
Bell TA. Chlamydia trachomatis, Mycoplasma hominis, and Ureaplasma urealyticum infections of infants. Semin Perinatol. 1985;9(1):29-37. PubMed 3881828.
Stamm WE, Wagner KF, Amsel R, et al. Causes of the acute urethral syndrome in women. N Engl J Med. 1980;303(8):409-415. PubMed 6993946.
Taylor-Robinson D, McCormack WM. The genital Mycoplasmas. N Engl J Med. 1980;302(18):1003-1010. PubMed 6988709.
Kim SJ, Lee DS, Lee SJ. The prevalence and clinical significance of urethritis and cervicitis in asymptomatic people by use of multiplex polymerase chain reaction. Korean J Urol. 2011;52(10):703-708.
Dong Q, Nelson DE, Toh E, Diao L, Gao X, Fortenberry JD, Van der Pol B. The microbial communities in male first catch urine are highly similar to those in paired urethral swab specimens. PLoS One. 2011;6(5):e19709.
Centers for Disease Control and Prevention. Recommendations for the laboratory-based detection of Chlamydia trachomatis and Neisseria gonorrhoeae—2014. MMWR Recomm Rep. 2014;63(RR-02):1–19.