Посев на аэробную и факультативно-анаэробную флору с определением чувствительности к антибиотикам и подбором минимальной подавляющей концентрации препарата

Aerobic and facultative anaerobic bacterial culture with antibiotic susceptibility testing (including MIC determination) isolates and identifies clinically significant bacteria from diverse specimen types and informs targeted therapy. The test also supports differentiation of aerobic versus anaerobic infection in the clinical workup when that distinction influences management. It is used in the evaluation of latent, low-grade, or chronic infectious processes by attempting recovery of persistent or difficult-to-culture organisms, and it guides antimicrobial selection through susceptibility profiling and MIC selection. Common synonyms include aerobic culture and bacterial culture with susceptibility testing.

Anaerobes are organisms that grow without oxygen; for many species, oxygen is toxic. They normally inhabit the gastrointestinal tract, respiratory tract, and genitourinary system. When host defenses are impaired or tissue is disrupted, endogenous anaerobes can drive infection; exogenous inoculation may also occur with deep puncture injuries, septic abortion, thoracoabdominal trauma, or placement of pins and prostheses. In soft tissues, clues to anaerobic involvement include tense edema, gas formation with subcutaneous crepitus, fetid odor, and putrid inflammation. Aerobic bacteria require free oxygen and generate energy through oxidative pathways. Successful culture of aerobes depends on appropriate media, controlled oxygen tension, and optimal incubation temperatures; each species has a characteristic range of oxygen concentrations that permits replication. Facultative anaerobes primarily use anaerobic metabolic routes but can grow in the presence of oxygen, in contrast to obligate anaerobes, which cannot survive exposure to oxygen. Facultative organisms derive energy by breaking down organic or inorganic substrates. Culture-based evaluation helps distinguish aerobic from anaerobic infection, as treatment approaches differ. After growth, organisms are identified and then tested for antimicrobial susceptibility. Because antimicrobial resistance is increasingly prevalent, empiric selections based solely on expected spectra may be ineffective. Determining susceptibility, including MIC values, helps select the most active agent for the specific isolate.