Mochevina azoti, 24 soatlik siydik
Kod:7005|CPT:84540|LOINC:3095-7, 3096-5
| Kabi | Mochevina azoti, siydik (U) Mochevina azoti, 24 soat |
|---|
Tahlil ma'lumotlari
Tadqiqot usuli
- Fermentativ ureaza usuli
Kutilayotgan natija topshirish vaqti
1 kun
Maxsus tayyorlik
- Document the total 24‑hour urine volume on the test requisition.
- Avoid alcohol for 24 hours before starting the collection.
- For 12 hours before collection, refrain from spicy or salty foods and items that discolor urine (eg, beetroot, carrots).
- If clinically acceptable, discontinue diuretics 48 hours before collection.
- Minimize physical and emotional stress throughout the 24‑hour collection period.
Qanday foydalanish
Mochevina azoti, 24 soatlik siydik (siydikdagi mochevina azoti, UUN) oqsil almashinuvi va azot balansini, jumladan azot balansi tadqiqi davomida, baholash uchun qo'llaniladi. Enteral yoki parenteral ovqatlantirish olayotgan og'ir ahvoldagi bemorlarda davom etayotgan oqsil katabolizmini taxminlashga yordam beradi va oziqlantirish qo'llab-quvvatlovi vaqtida oqsil kiritilishini moslashtirishga yo'naltiradi. Tahlil, shuningdek, qondagi mochevina oshganida yordamchi ko'rsatkich sifatida xizmat qilib, buyrakning ekskretor funksiyasini va buyrakning mochevinani chiqarish qobiliyatini baholashga hissa qo'shadi.
Cheklovlar
Mochevina (urea), uglerod kislotasining amididir; u jigar urea (ornitin) sikli orqali amin azotining utilizatsiyasining yakuniy mahsulotidir; bu sikl toksik ammiakni buyrak orqali chiqarilishi uchun suvda eruvchan mochevinaga aylantiradi. Mochevina glomerulda erkin filtrlanadi; filtrlangan yuklamaning taxminan uchdan biri passiv naychacha qayta so'rilishiga uchraydi; siydik oqimi kamayganda bu jarayon kuchayadi. Mochevina chiqarilishi ratsiondagi oqsil iste'moli bilan parallel. Azot muvozanati holatida, kuniga taxminan 500 mmol mochevina (≈14 g mochevina azoti) chiqarilishi taxminan 100 g oqsil iste'mol qilishga mos keladi. Siydikdagi jami azotning taxminan 90% ini mochevina tashkil etadi. Siydik orqali mochevina chiqarilishining ortishi manfiy azot balansini ko'rsatadi; bu operatsiyadan keyingi katabolizm, tirotoksikoz yoki yuqori oshqozon-ichak yo'llaridan qon ketishidan so'ng qon oqsillarining ichak orqali so'rilishi bilan kuzatilishi mumkin. Aksincha, siydikdagi mochevina kamayishi ijobiy azot balansini yoki mochevina ishlab chiqarilishi yoxud klirensining buzilganini aks ettiradi. Past qiymatlar buyrak kasalliklarida, mochevina sintezini cheklovchi jigar kasalliklarida va urea sikli fermentlarining tug'ma yetishmovchiliklarida uchraydi. Gipovolemiya yoki degidratatsiya davrida naychachalar qayta so'rilishining kuchayishi va buyrak perfuziyasining pasayishi—masalan, massiv qon ketish, shok, kuyishlar yoki yurak yetishmovchiligi—ham siydikdagi mochevina miqdorini kamaytiradi; aterosklerotik buyrak arteriyasi kasalligi bo'lgan yoshi katta bemorlarda buyrakka qon oqimining surunkali pasayishi tez-tez uchraydi.
| O'lchov birligi | mg/24h |
|---|---|
| Referens oraliq | — |
| Ko'rsatmalar | Evaluate nitrogen balance in critically ill patients receiving enteral or parenteral nutrition., Guide protein supplementation targets during nutrition support in critically ill populations., Adjunctive assessment of diminished renal excretory function in kidney disorders (eg, pyelonephritis, glomerulonephritis, renal amyloidosis, renal tuberculosis) and in acute or chronic kidney failure when blood urea is elevated. |
Natija og'ishlarining mumkin sabablari
Oshgan daraja
- cortisone
- dexamethasone
- hydrocortisone
- prednisolone
- quinine
- salicylates
- thyroxine
Pasaygan daraja
- anabolic steroids
- growth hormone
- insulin
- nephrotoxic drugs
- testosterone
Namunangiz talablari
| Namunangiz | Urina |
|---|---|
| Container | Steril siydik idishi |
| Hajm | 10 mL (min 1 mL) |
| Saqlash tayyorlik | Xona harorati, Sovutilgan, Muzlatilgan |
References
Kamyshnikov VS. Clinical Laboratory Tests from A to Z and Their Diagnostic Profiles. Reference manual. Moscow: MEDpress-inform; 2007. 3rd ed.
Marshall J. Clinical Biochemistry. Moscow; St. Petersburg: Binom; Nevskiy Dialekt; 2000.
Landry DW, Bazari H. Approach to the patient with renal disease. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011: Chap 116.